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2-Minute Neuroscience: Long-Term Potentiation (LTP)

Neuroscientifically Challenged 482 views

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is this like 7 minute abs? I think I'm gonna invent the 1 minute 45 second neuroscience channel
Comment from : @calebbryson-tt3ti

How do I increase AMPA and NMDA receptors?⭕️⭕️
Comment from : @1c_8q

How do I increase AMPA and NMDA receptors?
Comment from : @1c_8q

It's THAT simple My prof could never thank you! you're helping me through uni :')
Comment from : @frozenmangochunk

God bless you!!!!br🙏🙏🙏🙏🙏🙏🙏
Comment from : @dudacristelli4884

In a twist of fate, a system error directed the transaction to an invalid email address
Comment from : @Kenneth__q8

Does the act of recalling a memory or concept triggers long term potentiation, or is there any other specific requirements? Does that mean if you recall a topic frequently it would become a stronger memory, or does recalling the same thing not "strong" enough to trigger LTP?
Comment from : @pied6

Can dietary magnesium occupy the NMDA slot so that depolarization doesnt occur ?
Comment from : @johnathanabrams8434

Amazing!
Comment from : @HemanoRecords

💯💯💯💯💯💯💯💯❤️
Comment from : @kjy05

Would be nice to explain NMDA receptor and excess glutamate excitotoxicity so people don't start downing glutamine on mass to increase LTP Or other things that may cause excitotoxicity
Comment from : @hardcorestymie

beautiful explanation
Comment from : @DhanAadian

So, does this raise the threshold when it happens again?
Comment from : @mattaku9430

it seems LTP comes in collage, so why i am i studin it in 10th reason : cus its fun thanks for the concept br
Comment from : @atharvpateriya3721

lol
Comment from : @giantswin-die

Ok, so AMPA receptors respond to glutamate and cause depolarization But its not all or nothing More AMPA receptors cause a greater depolarization, or a faster depolarization But definitely increase sensitivity to glutamate Is this because the receptors only respond to glutamate in a very small area? So more receptors will cause the cell to respond to the amount of glutamate released more accurately, by allowing it to cover a wider area and respond to a higher percentage of the actually released glutamate? Or do the receptors only allow a very small amount of ions through? Meaning more receptors just means that when they DO activate, more ions are allowed through, speeding up depolarization?
Comment from : @joshuamiller7502

Not well explained
Comment from : @rgudduu

Beautifully explained!
Comment from : @steviesynapse

love u thanks for this
Comment from : @luisam1329

I just really couldn't say how much really this simple brief video made me really understand every point of the book explaining this kind of LTP mechanism , from the middle east Jordan university , rehabilitation college , 2nd year ,,,,,,,salutes to you
Comment from : @psjfree9974

Hi, my lecturer said something about EPSP being greater with protein synthesis inhibition Can you explain why?
Comment from : @pearl4808

Thank you so much It's very useful
Comment from : @misschanhauying

Very nicely done! thank you!
Comment from : @AndrewP-zi5ht

Тow I understand why it is necessary to constantly repeat what I have learned
Comment from : @КатеринаЛевченко-р4б

The fact that I can understand these videos in great detail while doing indica edibles means you're doing a good job of explaining it lmao GREAT CHANNEL!!!!!!!!!
Comment from : @poisedperson6475

Thank you! I finally understand it
Comment from : @jenzar

The plug
Comment from : @jjbbabby

thank you so much, I got stuck on what was happening with the AMPAR's - this video really helped
Comment from : @qp5337

see, I had to watch at 075x speed but this makes so much more sense than the lecturer & the 4 neurosci books thanks!
Comment from : @doorbella1357

fantastic - thank you
Comment from : @sweetpea7270

What is the signaling mechanism that increases the neurotransmitter release?
Comment from : @god-son-love

Great explanation
Comment from : @dailydoseofmedicinee

Thankyou very muchbrIt's short but it's very amazing and completely
Comment from : @امیرمحمدزند-ص6و

YOURE AN ANGEL SENT FROM ABOVEE
Comment from : @sarahsh9383

1 minute if i put it in 2x speed
Comment from : @adriannazhang2096

dude, this is just incredible! That is definitely the fastest and most easy to follow explanation of LTP I've seen! Thanks a lot!
Comment from : @krahul5910

#AmityBumble_ in ≈Autumn 2019brDue to #LongTermPotentiation
Comment from : @glotmath

But how neuron "sense" there is lack of AMPA receptors , i mean how calcium influx creating new receptors ?
Comment from : @zahiddogan

When my assignment is due in one hour so I have to watch this at "05-Minute Neuroscience" speed instead
Comment from : @penelopestuart5032

Wow thank you for this video
Comment from : @katgerasimenko8800

My lecturer who is experienced in the field of neuroscience took 15 minutes to explain this concept in the most convoluted and confusing way possible and no one understood it It took you 2 minutes to explain it in a clear and simple way and now it makes sense Thank you
Comment from : @YellowSub0

Firstly, I love your work (is there an echo in here?) It'd b great to have one separating E-LTP from L-LTP
Comment from : @toekneesee

Thanks I always appreciate the clarity brevity and effort you give There’s a lot of hard work in your short clips 👍👏👏
Comment from : @ericwieckmann4096

Great video!
Comment from : @sravyapailla923

Would all APs active NDMA? Or would it require multiple/high frequency APs?
Comment from : @JscWilson

I still dont get it Someone explain
Comment from : @TheVaultofContent

very informative, thank you
Comment from : @ryanlevin1912

But what does calcium do in peticular?
Comment from : @Martin-dw4eo

Hi, Does this only happen when glutamate is the neurotransmitter or it can also happen when dopamine is the neurotransmitter used? If it is only for glumate, do you know any other mechanisms which causes Long Term Potentiation in dopaminergic synapses? Thank you
Comment from : @adriangil6012

Khan academy
Comment from : @chanbrickybud

watching this video gave me LTP in my brain ABOUT LTP
Comment from : @malignantsparrow5892

Glycine is also involved with the NMDA receptors
Comment from : @timov13

More detail - LTP involves the PKC and CaMKII PKC will phosphorylate AMPA receptors at the S818 GluR1 subunit, and CaMKII will phosphorylate the S831 GluR1 subunit This increases opening probability and also helps to recruit more AMPA receptors into the postsynaptic terminal
Comment from : @warren2502

I just came across this series of videos! Brilliant! I wish I had found them at the beginning of my graduate degree
Comment from : @vastaik12

So concise and easy to follow Keep it up this is awesome
Comment from : @chrismcgeoghegan7059

IM SO DUMB but this helps
Comment from : @eloisecobby-smith5058

What an awesome video! I was taught that the EPSP resulting from the activation of local AMPA receptors does not produce a strong enough depolarization to expel the magnesium plug and that it is actually a back-propagating action potential generated by the axon hillock that provides the necessary depolarization to remove the magnesium ion Am I mistaken?
Comment from : @CamaroMD

Such a good video
Comment from : @NealThakkar1993

rtu
Comment from : @BeatsByClover

Moon man moon man here we come
Comment from : @BeatsByClover

amazing video!!! subscribed <3
Comment from : @janicceee

Thank you Needed to learn this quick for my final
Comment from : @isabelokoro

Our brains are so amazing You made a video about LTP that was memorable and caused LTP in my neurons so that they are more sensitive to impulses which arise when I think about LTP
Comment from : @soulsunshine108

I've never commented on a Youtube video in the 10 years I've been using it, but this is straight up incredible work Keep em coming
Comment from : @ninooshea9232

Hi! I was wondering what the positive ions were that enter the AMPA receptors? This was wonderful though - thank you!
Comment from : @taytayswizzlez13